To reset all settings of Python in Ubuntu, you can try the following steps:

1. Close any open Python programs or shells.

2. Open a terminal and run the following command to remove all global packages:

pip freeze | xargs pip uninstall -y

3. Run the following command to remove the Python package manager (pip):

sudo apt-get remove python3-pip

4. Run the following command to remove the Python interpreter:

sudo apt-get remove python3

5. Run the following command to update the package list:

sudo apt-get update

6. Run the following command to install the latest version of Python:

sudo apt-get install python3

7. Run the following command to install the Python package manager (pip)

sudo apt-get install python3-pip

These steps should reset all settings of Python on your Ubuntu system. Note that this will remove all global packages and any custom configurations you have made to your Python environment.